disseminated cryptococcus india ink stain

Cryptococcal antigens may also be detected in the CSF and serum. DiagnosisĮncapsulated budding forms of the fungus may be seen in the cerebrospinal fluid (CSF), urine or pus using Indian ink staining. gattii is more commonly seen in immunocompetent people. neoformans is more commonly seen in immunocompromised people C. Untreated meningitis can be fatal in weeks to months.Ĭ. Immunocompromised people (including those with HIV infection or cancer) often present with meningitis (subacute or chronic) and may have disseminated infection at other sites, including kidneys, prostate, bone and skin, in the form of pustules, papules, plaques and ulcers. Pulmonary cryptococcosis in immunocompetent people usually manifests as a nodule, which must be distinguished from a malignancy however, malignancies may co-exist. Skin, bone and other organs are less frequently infected. Lung involvement may cause symptoms of lower respiratory tract infection or may be asymptomatic. Identification of cryptococcosis Clinical featuresĬryptococcal infection usually presents as subacute or chronic meningitis or meningoencephalitis with headache and altered mental state. gattii has been associated with some tree species (eucalyptus) its natural habitat is soil and plant debris. The major species of Cryptococcus include C. Infection occurs after inhalation of spores that are present in the environment. Infectious agent of cryptococcosisĬryptococcu s is a fungus that is found in soil and is usually associated with bird droppings. Primary school and children’s services centre exclusion for cryptococcosis Notification requirement for cryptococcosis

Disseminated cryptococcus india ink stain